EndothelialCells相关论文
Establishment of an in vitro safety assessment model for lipid-lowering drugs using same-origin huma
Cardiovascular safety assessment is vital for drug development,yet human cardiovascular cell models are lacking.In vitro......
Endothelial cells play an obligatory role in regulating local vascular tone and maintaining homeostasis in vascular biol......
皮肤恶性黑色素瘤(CMM)是一种早期即可发生淋巴转移,预后严重不良的侵袭性恶性皮肤系统肿瘤。其淋巴转移机制非常复杂,涉及到细胞运动......
Study on the protective effect of Tadehaginoside on the damage of endothelial cell mitochondria indu
ABSTRACT Objective: To investigate the protective effect of Tadehaginoside on vascular endothelial cell injury induced b......
目的:观察头部督脉排刺法治疗脑卒中后失眠的临床疗效,分析患者睡眠结构、血清氨基酸类神经递质、血管内皮细胞功能及认知功能的变......
Nuclear factor kappa B (NF-κB) activation contributes to many vascular inflammatory diseases.The present study tested t......
Caffeine induces multiple vascular effects.In this study we investigated the angiogenic effect of physiological concentr......
Effect of Songlingxuemaikang(松龄血脉康)on mild essential hyper-tension in patients:a randomized parallel
OBJECTIVE:To evaluate the effect of songlingxue-maikang(松龄血脉康,SLXMK) on mild essential hy-pertension in patients in......
目的 了解间充质干细胞(MSC)分化为内皮细胞的可能的调控机制,以促进其在未来临床实践中的应用?研究目标是脐带来源的间充质干细胞......
The influence of laminar flow on the corrosion of pure zinc (Zn) and cell response was investigated and compared with th......
Intracellular calcium ions facilitate dengue virus entry into endothelial cells and compromise endot
Objective: To investigate the involvement of Ca2+ in dengue virus (DENV)-infected human umbilical vein endothelial cells......
Majority of cancer patients die from cancer metastases.The physical stimulation produced by microenvironment regulates i......
Xuebijing Injection(血必净注射液)Increases Early Survival Rate by Alleviating Pulmonary Vasopermeability i
Objective:To investigate the effects of Xuebijing Injection(血必净注射液,XBJ) on survival rate and pulmonary vasopermeab......
Early intervention with Didang decoction delays macrovascular lesions in diabetic rats through regul
The study aimed to investigate the intervening role of Didang decoction (DDD) at different times in macrovascular endoth......
The surface construction by heparin-poly-l-ly-Sine (Hep-PLL) nanoparticles loaded VEGF and biocompat
The late thrombosis and restenosis threat seriously to human health after implantation of vascular stent up to now. The ......
PEI-g-P(LA-co-MMD)-g-PEI nanoparticles as gene carriers to promote the proliferation of human vascul
Polyethylenimine (PEI) is one of the most efficient and widely studied synthetic carriers,which have been proven to be a......
Polyethylenimine (PEI) is one of the most successful cationic polymers for gene delivery.PEI of high molecular weight pr......
Copper uptake by DMT1:A compensatory mechanism for CTR1 deficiency in human umbilical vein endotheli
Copper transport 1(CTR1)plays a critical role in copper uptake by cells,1 but several studies demonstrated that divalent......
VCAM-1-targeted silica nanoparticles doped with FITC and Fe3O4 for dual-mode cellular imaging of LPS
Multi-modality and specific targeting nanoprobes are emerging as an ideal tool for labeling,intracelhlar tracking,molecu......
Objective:The present study was designed to test the hypothesis that Ligustrazin can inhibit hydrogen peroxide (H2O2)-in......
Activation of Nrf2 and PPARy plays a role in the genistein-mediated attenuation of oxidative stress-
We investigate the cytoprotective effects and molecular mechanism of genistein in oxidative stress-induced injury using ......
Endothelial cells enumeration in peripheral blood of patients underwent hepatectomy-Preliminary resu
Objective The purpose of this study.Liver cancer,primarily hepatocellular carcinoma,is the 5th most common cancer and th......
Pericytes are essential to vascularization,but the purification and characterization of pericytes remain unclear.Smooth ......
CD226 Molecule Involved in Type 2 Diabetes Mellitus via Modulating Glucose Uptake in Endothelial Cel
CD226 is a co-stimulatory adhesion molecule that was previously defined on immune cells.Recently, emerging evidence indi......
Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MAPK phosphatase
Aim: Inflammation and vascular perturbations are increasingly implicated in the pathogenesis of neurodegenerative diseas......
Dihydrotanshinone Ⅰ inhibits LPS induced LOX-1 expression via TLR4/ROS/NF-κB signal pathway in human
Aim: Lectin-like receptor for oxidized low density lipoprotein (LOX-1) has been implicated as the main receptor for oxid......
Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial c
Aim: Accumulating evidence implicates that the endothelial injury contributes to the ischemic neurovascular damage.This ......
Inward rectifier K+ currents are regulated by CaMKⅡ in endothelial cells of primarily cultured bovin
Endothelium lines vascular walls and regulates vascular tones.The endothelial cells sense and respond to chemical and me......
Migration Behavior of Endothelial Cells in 3D Biomaterials to Mimic the Repair of Blood Vessels in V
Cell migration plays a crucial role in a variety of physiological and pathological processes ranging from wound healing,......
Effect of Icariside Ⅱ on miR-126 pathway on human cavernous endothelial cells exposed to a diabetic-
Background: To investigate the status of miR-126 and its targeting Spred1 under the stimulation of glucose and Age-BSA a......
Activation of α7 nicotinic acetylcholine receptor protects against oxidant stress damage through red
Aim Alpha7 nicotinic acetylcholine receptor (a7nAChR), a subtype of nAChR regulating neurotransmission in central nervou......
Molecular biology for genitourinary system diseases and sexual dysfunction icariside Ⅱ prevents high
Objective: Dysfunction of human cavernous endothelial cells(HCECs)is a common pathological alteration caused by elevated......
This research was aimed to investigate the anti-inflammatory mechanism of acetylharpagide extracted from Ajuga decumbens......
Endothelial cells, which line in the interior surface of all blood vessels, are involved in many aspects of physiologica......
Protective Effects of Human Induced Pluripotent Stem Cell-Derived Exosomes on High Glucose-Induced I
Patients with type 2 diabetes mellitus are at an extremely high risk for developing life-threatening cardiovascular comp......
HSPA12B protects endothelial cells against endotoxin challenge by inhibiting p38 MAPK phosphorylatio
Endothelial barrier dysfunction is the hallmark of acute lung injury or acute respiratory distress syndrome, involving c......
Intercellular communication through gap junctions plays an essential role in maintaining the functional integrity of vas......
Inhibitory effect of rosiglitazone on C-reactive protein production induced by angiotensinⅡ in human
OBJECTIVE To observe the effects of rosiglitazone on signaling pathway of angiotensin Ⅱ (Ang Ⅱ)-induced C-reactive pro......
A natural squamosamide derivative FLZ inhibits homocysteine-induced rat brain microvascular endothel
OBJECTIVE Compound FLZ is a novel synthetic squamosamide cyclic analogue with several phenolichydroxy groups.Previous re......
The crosstalk between nitrosative stress and cellular autophagy-lysosome process in endothelial cell
OBJECTIVE The present study was desighed to determine the causative links and precise correlations among nitrosative str......
Xiaokening stimulates nitric oxide release from the endothelial cells in mesenteric arterioles in th
...
We have observed that iron uptake into bovine aortic endothelial cells is via two parallel pathways.Via,either L or T ty......
Design, synthesis and the mechanism of anti-atherosclerosis of The novel Tetramethylpyrazine derivat
Tetramethylpyrazine (TMP),the active ingredients of Chinese traditional medicine Chuanxiong with effect promoting blood ......
TMEM16A contributes to endothelial dysfunction by facilitating Nox2 NADPH oxidase-derived reactive o
Ca2+-activated Cl- channels play a crucial role in various physiological processes.However,the role of TMEM16A in vascul......
Potential proinflammatory effects of hydroxyapatite nanoparticles on endothelial cells in a monocyte
Objective:Synthetic hydroxyapatite nanoparticles (HANPs) are widely used in nanomedicine fields.The delivery of nanomedi......
High mobility group box-1 (HMGB1),has been implicated as a pro-inflammatory cytokine in the pathogenesis of various infl......
Aim: Angiogenesis contributes to ischemic, inflammatory, infectious and immune disorders and also occurs during numerous......
Development of a New Method for Isolation and Culture of Pulmonary Arterial Endothelial Cells from R
Pulmonary endothelial dysfunction plays an integral role in the pathogenesis and development of pulmonary hypertension.H......
The Changes of Inflammatory Cytokines Induced by The Interaction of Endothelial Cells and Polymorpho
Objective To investigate the changes of IL-8 and ICAM-1 induced by the interaction of endothelial cells and polymorphonu......
Transient receptor potential (TRP) channels function as cellular sensors to perceive and respond to a variety of environ......